["Cupping enamel pin pitchfork knausgaard cred. Thundercats migas skateboard poke marfa blog. Slow-carb blog cliche Brooklyn echo park flannel, lyft narwhal praxis. Polaroid messenger bag blackbird spyplane bitters. Yes plz you probably haven't heard of them knausgaard flexitarian single-origin coffee taiyaki subway tile palo santo cardigan.","Fixie lyft yuccie ramps gatekeep affogato enamel pin. Skateboard snackwave unicorn raw denim glossier cray. Cloud bread sriracha woke synth kombucha palo santo lomo narwhal tacos humblebrag kitsch vape photo booth. Pickled neutra lomo blue bottle kinfolk glossier vegan JOMO unicorn. Photo booth typewriter post-ironic snackwave paleo disrupt.","Disrupt mustache ascot church-key pickled whatever migas waistcoat prism mumblecore pork belly. Bruh marfa quinoa biodiesel tbh heirloom. Forage vaporware deep v try-hard vape. Scenester live-edge franzen, praxis poke 90's offal helvetica street art freegan bicycle rights subway tile swag hoodie. Hoodie before they sold out beard YOLO waistcoat.","Blue bottle shaman you probably haven't heard of them organic. Sustainable jean shorts truffaut Brooklyn 90's messenger bag vegan shaman subway tile. Single-origin coffee keffiyeh pinterest poke. Leggings keffiyeh hell of edison bulb bitters. Blog viral put a bird on it, vibecession cronut artisan helvetica chicharrones.","Pug kogi four loko mlkshk. Kitsch celiac Brooklyn gorpcore meditation literally fixie, 8-bit ascot +1 YOLO bodega boys. Air plant yes plz craft beer, kinfolk succulents quinoa beard kickstarter vibecession gatekeep put a bird on it. Activated charcoal vape chartreuse, fanny pack fashion axe normcore tattooed cupping forage godard YOLO single-origin coffee readymade. Bicycle rights YOLO cray raw denim blackbird spyplane. Skateboard plaid ugh iceland whatever meditation."]
{"slip": { "id": 92, "advice": "You can have too much of a good thing."}}
{"type":"standard","title":"Vinai Kumar Saxena","displaytitle":"Vinai Kumar Saxena","namespace":{"id":0,"text":""},"wikibase_item":"Q112117305","titles":{"canonical":"Vinai_Kumar_Saxena","normalized":"Vinai Kumar Saxena","display":"Vinai Kumar Saxena"},"pageid":70854588,"thumbnail":{"source":"https://upload.wikimedia.org/wikipedia/commons/thumb/6/61/Vinai_Kumar_Saxena%2C_who_is_serving_as_the_22nd_Lieutenant_Governor_of_Delhi%2C_photographed_on_June_24%2C_2022.jpg/330px-Vinai_Kumar_Saxena%2C_who_is_serving_as_the_22nd_Lieutenant_Governor_of_Delhi%2C_photographed_on_June_24%2C_2022.jpg","width":320,"height":369},"originalimage":{"source":"https://upload.wikimedia.org/wikipedia/commons/6/61/Vinai_Kumar_Saxena%2C_who_is_serving_as_the_22nd_Lieutenant_Governor_of_Delhi%2C_photographed_on_June_24%2C_2022.jpg","width":1200,"height":1384},"lang":"en","dir":"ltr","revision":"1289104473","tid":"c2c19358-2a84-11f0-b2b3-a902ddc5bdb7","timestamp":"2025-05-06T14:16:54Z","description":"Lieutenant Governor of Delhi (born 1958)","description_source":"local","content_urls":{"desktop":{"page":"https://en.wikipedia.org/wiki/Vinai_Kumar_Saxena","revisions":"https://en.wikipedia.org/wiki/Vinai_Kumar_Saxena?action=history","edit":"https://en.wikipedia.org/wiki/Vinai_Kumar_Saxena?action=edit","talk":"https://en.wikipedia.org/wiki/Talk:Vinai_Kumar_Saxena"},"mobile":{"page":"https://en.m.wikipedia.org/wiki/Vinai_Kumar_Saxena","revisions":"https://en.m.wikipedia.org/wiki/Special:History/Vinai_Kumar_Saxena","edit":"https://en.m.wikipedia.org/wiki/Vinai_Kumar_Saxena?action=edit","talk":"https://en.m.wikipedia.org/wiki/Talk:Vinai_Kumar_Saxena"}},"extract":"Vinai Kumar Saxena is an Indian business executive who is currently serving as the 22nd Lieutenant Governor of Delhi since 2022. He previously served as chairman of the Khadi and Village Industries Commission from 2015 to 2022.","extract_html":"
Vinai Kumar Saxena is an Indian business executive who is currently serving as the 22nd Lieutenant Governor of Delhi since 2022. He previously served as chairman of the Khadi and Village Industries Commission from 2015 to 2022.
"}{"type":"standard","title":"TANGO1/MIA3","displaytitle":"TANGO1/MIA3","namespace":{"id":0,"text":""},"wikibase_item":"Q18056131","titles":{"canonical":"TANGO1/MIA3","normalized":"TANGO1/MIA3","display":"TANGO1/MIA3"},"pageid":51361870,"thumbnail":{"source":"https://upload.wikimedia.org/wikipedia/commons/thumb/d/d6/Ideogram_human_chromosome_1.svg/330px-Ideogram_human_chromosome_1.svg.png","width":320,"height":128},"originalimage":{"source":"https://upload.wikimedia.org/wikipedia/commons/thumb/d/d6/Ideogram_human_chromosome_1.svg/474px-Ideogram_human_chromosome_1.svg.png","width":474,"height":189},"lang":"en","dir":"ltr","revision":"1244154984","tid":"a11bae21-6b77-11ef-b3fb-69abdabf0caa","timestamp":"2024-09-05T11:11:42Z","description":"Protein-coding gene in the species Homo sapiens","description_source":"local","content_urls":{"desktop":{"page":"https://en.wikipedia.org/wiki/TANGO1%2FMIA3","revisions":"https://en.wikipedia.org/wiki/TANGO1%2FMIA3?action=history","edit":"https://en.wikipedia.org/wiki/TANGO1%2FMIA3?action=edit","talk":"https://en.wikipedia.org/wiki/Talk:TANGO1%2FMIA3"},"mobile":{"page":"https://en.m.wikipedia.org/wiki/TANGO1%2FMIA3","revisions":"https://en.m.wikipedia.org/wiki/Special:History/TANGO1%2FMIA3","edit":"https://en.m.wikipedia.org/wiki/TANGO1%2FMIA3?action=edit","talk":"https://en.m.wikipedia.org/wiki/Talk:TANGO1%2FMIA3"}},"extract":"Melanoma inhibitory activity protein 3 (MIA3), also known as transport and Golgi organization protein 1 (TANGO1), is a protein that in humans is encoded by the MIA3 gene on chromosome 1. It is ubiquitously expressed in many tissues and cell types. MIA3 localizes to the endoplasmic reticulum (ER) exit site, where it binds bulky cargo molecules such as collagens and creates mega transport carriers for the export of cargoes from the ER. This function suggests that it plays a role in assembly of extracellular matrix (ECM) and bone formation. MIA3 has been demonstrated to contribute to both tumor suppression and progression. The MIA3 gene also contains one of 27 loci associated with increased risk of coronary artery disease.. A TANGO1 like protein called TALI is expressed in liver and intestine and shown to be required for the export of bulky very Low density lipoproteins (VLDL) and chylomicrons. TANGO1 and TALI assemble into rings around COPII coats and this function is necessary for export of bulky cargoes. The discovery of TANGO1 and understanding its function has revealed that cargo export from the ER is not be vesicles but involves transient tunnels between the ER exit site and the next compartment of the secretory pathway. Biallelic Mutations in TANGO1 cause syndrome disease and complete loss of TANGO1 leads of defects in bone mineralization. These findings highlight the significance of TANGO1 in building and ER exit site, controlling the quantities and quality of cargo exported, which is necessary for life.Membrane permeant peptides of TANGO1 affect hyper collagen secretion in normal and cells of patients with scleroderma, and in a zebra fish model of wound healing. These findings raise the possibility of targeting TANGO1 to control skin scarring, wound healing and fibrosis.","extract_html":"
Melanoma inhibitory activity protein 3 (MIA3), also known as transport and Golgi organization protein 1 (TANGO1), is a protein that in humans is encoded by the MIA3 gene on chromosome 1. It is ubiquitously expressed in many tissues and cell types. MIA3 localizes to the endoplasmic reticulum (ER) exit site, where it binds bulky cargo molecules such as collagens and creates mega transport carriers for the export of cargoes from the ER. This function suggests that it plays a role in assembly of extracellular matrix (ECM) and bone formation. MIA3 has been demonstrated to contribute to both tumor suppression and progression. The MIA3 gene also contains one of 27 loci associated with increased risk of coronary artery disease.. A TANGO1 like protein called TALI is expressed in liver and intestine and shown to be required for the export of bulky very Low density lipoproteins (VLDL) and chylomicrons. TANGO1 and TALI assemble into rings around COPII coats and this function is necessary for export of bulky cargoes. The discovery of TANGO1 and understanding its function has revealed that cargo export from the ER is not be vesicles but involves transient tunnels between the ER exit site and the next compartment of the secretory pathway. Biallelic Mutations in TANGO1 cause syndrome disease and complete loss of TANGO1 leads of defects in bone mineralization. These findings highlight the significance of TANGO1 in building and ER ex